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Cowpea (Vigna unguiculata) is a resilient and versatile legume cultivated particularly in arid and semi-arid region and play significant role in food security. A study was conducted to evaluate efficacy of foliar application of boron and soil application of zinc levels on growth and yield of cowpea. The experimental field was laid out in Randomized Completely Block Design with 10 treatments including 3 levels of boron (1kg ha-1 ,2kg ha-1, 3kg ha-1), 3 level of zinc (10kg ha-1, 20kg ha-1, 30kg ha-1) along with its combination and replicated thrice during 20th March to 13th june,2023 at Lamahi Municipality, Dang district of Lumbini Province. During research, Malepatan-1 Variety was used where effect of treatments was observed on parameters like plant height, number of branches, days to flowering, pod length, pod diameter, number of seed per pod, thousand grain weight and yield. The result showed there is significance effect on plant height, no. of branches, thousand grain weight and grain yield whereas pod length and pod diameter remain nonsignificant throughout the research. Combined application of RDF + B (2kg ha-1) + Zn (20kg ha-1) showed maximum plant height i.e. 21.5cm at 45 DAS, RDF + B (1kg ha-1 ) + Zn (10kg ha-1) 32.7cm at 60 DAS and RDF + B (3kg ha-1) + Zn(30kg ha-1) 55cm at 75 DAS whereas, treatment RDF + B (3kg ha-1) + Zn (30kg ha-1) showed maximum number of branches 4,5,and 6 at 45DAS, 60DAS and 75DAS respectively. Similarly, in treatment RDF + B (3kg ha-1) + Zn (30kg ha-1) maximum number of seed per pod i.e. 14, maximum thousand grain weight of 150.8g and maximum grain yield of 1.2kg was observed.