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The study was conducted to determine the effect of diets containing biochar and clay on the hematological
indices, serum biochemistry and total bacterial viable count of broiler. Ninety six broilers were allocated to four treatments diets having three replicates of eight broilers in a completely randomized design. Data were collected on red blood cell count (RBC), white blood cell count (WBC), hemoglobin concentration (Hb), hematocrit (HCT), platelets count, lymphocytes, mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC) levels, creatinine, total protein, total cholesterol, albumin, globulin, urea, Alanine amino transferase (ALT), Aspartate Aminotransferase (AST) and triglyceride in broiler chickens. Results showed that there were significant (p < 0.05) differences in all the serum indices and hematological parameters determined in this study. Treatment 4 had the highest white blood cell count, lymphocytes, hematocrit but the lowest creatine and bacteria viable count while treatment 1 had the lowest platelets but the highest bacteria viable count. The T4 diets containing clay and biochar at 2.5% inclusion levels each improved the indices of broiler better than the other treatments used in this experiment. This implies that T4 diets had the greatest capacity to bind the toxins contained in the feed.