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Wheat is one of the staple foods of the Nepalese diet which is grown in the winter season in most of the areas of our country. This short review article analyses the previous works and studies to investigate the role of various micro and macronutrients in wheat crops. Long-time research which was conducted in several locations has shown that in addition to natural resource deterioration and biotic-abiotic stress, deficiency of multiple nutrients is also an essential factor that influences yield reduction, productivity declination, and shrinkage in net profit. Therefore, Integrated Nutrient Management in terms of using chemical fertilizers in conjugation with organic manures as well as biological inputs is needed to improve the nutrient status of the soil. INM increases the nutrient uptake rate of the plant and influences the nutrient supply in the soil system. As soil is the primary source of nutrients, any degradation in the quality of soil can create a reduction in crop yield. Hence the adoption of suitable measures is highly necessary for sustaining the environment and enhancing productivity.